Titration: dose of carbimazole is titrated to keep thyroid hormone levels within the normal range.There are also two methods to administer ATDs: 3 Carbimazole and propylthiouracil are the two options, but carbimazole is preferred due to the increased side effects of propylthiouracil in children. Management Initial management of Graves’ diseaseġ st line management is medical treatment with anti-thyroid drugs (ATDs). Pretibial myxoedema – indicative of Graves’ disease.Signs of thyroid eye disease – exophthalmos, ophthalmoplegia, lid retraction, lid lag (can cause dry eyes).Tachycardia (rarely SVT), wide pulse pressure.Goitre (bruit) that will move on swallowing but not on tongue protrusion (Figure 3).Delayed or accelerated puberty oligo or amenorrhoea. ![]() Learning difficulties, behavioural problems, decreased concentration.Therefore, an imbalance of hormones can affect many systems in the body. Thyroid hormone is essential for brain development, growth, and metabolism.
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